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oncology hemolytic mds activation agglutinin chronic cll cold extravascular hemolysis hodgkins icl infectiousdiseases intravascular leukemia lymphocytic lymphocytopenia lymphoma lymphopenia macrophage
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Diagnosis and Management ... cytopenias (usually anemia ... risk-stratification • Risks: infection ... #Diagnosis #Management ... #treatment #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... anemia Treatment ... #hematology #diagnosis ... #management
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
Idiopathic CD4 Lymphopenia ... Autoimmune (Sjogren, SLE ... /myelodysplasia) ... • Infections ... #hematology #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... CLL, lymphoma, idiopathic ... #differential # ... diagnosis #hematology ... #anemia
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
• Anemia • Aplastic ... Myeloproliferative Disease ... blood count with differential ... #Syndromes #diagnosis ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
(CAD): - Idiopathic ... Agglutinin Syndrome ... anemia • Cold ... younger pts) Differential ... #hematology #diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus [SLE ... ], AOSD) • Infection ... with leukopenia, anemia ... #Diagnosis #Management ... #Hematology #Rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Advanced HIV (CD4 ... Hematologic malignancy ... Bone Marrow - Anemia ... #differential #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
weeks without infection ... cells can indicate disease ... • Neutropenia, anemia ... Pure red cell aplasia ... workup #oncology #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... number of sites of disease ... Hodgkin Lymphoma Treatment ... #hematology #oncology ... #management
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