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management differential lupus reactions blood classification comparison dermatomyositis product syndrome systemic table transfusion vasculitis algorithm antibodies antimda5 antimda5dm antinuclear antinxp2
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Differential Diagnosis ... Kidney disease common ... Chronic B-cell activation ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... - Cytopenia: Common ... Evolution: Chronic disease ... #Summary #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Systemic lupus erythematosus ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
or more commonly ... GPA causes disease ... Rarely dominate the clinical ... Polyangiitis #GPA #dermatology ... #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Generally affects long ... XR, MRI to dx and ... dz difficult to see ... #differential #diagnosis ... #causes #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Bronchiectasis - Permanent dilation of an airway WHAT CAN YOU SEE ON CT? 1) Lack of tapering of
ON CT? ... ) WHAT ARE COMMON ... /Autoimmune diseae ... Bronchiectasis #pulmonary ... #diagnosis #differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... [SLE], AOSD) • ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Systemic Lupus Erythematosus ... Evolution: Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
activation • Timing ... without other cause ... CXR with pulmonary ... Transfusion #Reactions #hematology ... #diagnosis #comparison
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