16 results
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Differential Diagnosis ... Arthritis: • Joint ... arthropathy • 90% joints ... #Diagnosis #Rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... Systemic lupus erythematosus ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pulmonary ... • Interstitial lung ... , SLEPulmonary ... #differential #diagnosis ... #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... effusion, Restrictive lung ... pain (20%) Renal disease ... #systemic #erythematosus ... #rheumatology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Rarely dominate the clinical ... surfaces of the joints ... Polyangiitis #GPA #dermatology ... #rash #diagnosis ... #rheumatology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Generally affects long ... XR, MRI to dx and ... dz difficult to see ... #differential #diagnosis ... #causes #hematology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
: ILD (interstitial ... lung disease), ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... Granulomatous lymphocytic interstitial ... lung disease (GLILD ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Systemic lupus erythematosus ... (to support a diagnosis ... and RF (if clinical ... #testing #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... inflammatory lesions-interstitial ... systemic lupus erythematosus ... SLE) • Urinalysis ... #rheumatology #