7 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... erythematosus ... #ANCA #Antineutrophil ... #antibodies #diagnosis ... #rheumatology #
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (SLE), Systemic ... , Interstitial Pulmonary ... #Antibodies #ANA ... #patterns #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... • Anti-Ro/SSA autoantibodies ... , dermatomyositis ... Serositis Labs: • ANA ... #Diagnosis #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
inflammatory lesions-interstitial ... LFT • ESR • ANA ... ) pattern: antibodies ... , and SLE) • Urinalysis ... #rheumatology #
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... searched for when ANA ... #diagnosis #rheumatology ... #table #ANA
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Clinical history ... biliary, renal, lung ... concentration PET-CT ... (antinuclear antibodies ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... salivary ducts Clinical ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology