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differential erythematosus management vasculitis ana antinuclear associations autoantibodies classification common connectivetissuediseases ctild cvid hypogammaglobulinemia ild immunodeficiency immunology lungdisease mimickers myopathy
Connective tissue disease-associated interstitial lung diseases LIP: lymphoid interstitial pneumonia. NSIP: nonspecific interstitial pneumonia. OP: organizing pneumonia.
interstitial lung ... PSS: Sjogren syndrome ... : systemic lupus ... #Table #Pulmonary ... #Rheumatology #
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... (SLE), Systemic ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... ANA #patterns #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... of Systemic Lupus ... #SLE #systemic ... #symptoms #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Myositis 4% - Lung ... Auto-Antibodies ... #Systemic #Lupus ... #differential #rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... : ILD (interstitial ... lung disease), ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... rheumatologic diseases ... : • Symptoms limited ... #Systemic #Lupus ... #Rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... Nephrogenic DI Hematologic ... MALT Lymphoma • Lung ... #Rheumatology #
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... Chest CT: • Ground-glass ... hemolytic anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
as systemic lupus ... Symptoms (Sx) in ... purpura: strong sign ... vasculitis, and SLE ... #rheumatology #
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
lung disease Malignancy ... lung disease • ... lung disease • ... • Conduction system ... Myositis #Myopathy #rheumatology
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