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differential infectiousdiseases treatment classification vasculitis cardiology abscess activation aids antibodies antinuclear bronchiectasis conditions cryofibrinogenemia cryoglobulinemia cryoglobulins cvid erythematosus extrarticular fungal
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... , SLE • Pulmonary ... syndrome - SLE ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... likely it will be clinically ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Bronchiectasis - Permanent dilation of an airway WHAT CAN YOU SEE ON CT? 1) Lack of tapering of
ON CT? ... ) WHAT ARE COMMON ... /Autoimmune diseae ... Bronchiectasis #pulmonary ... #diagnosis #differential
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... Parenchyma: • Infection ... / Autoimmune: ANCA-Assoc ... Goodpasture's, SLE ... #pulmonary #causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... Kidney disease common ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... solid cancers • Autoimmune ... diseases: SLE++ ... #management #treatment ... #summary #rheumatology
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
verrucous) • Lung ... regurgitation • Autoimmune ... (SLE Libman Sacks ... Cerebral > Splenic, pulmonary ... #diagnosis #management
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... : • Clinical triad ... • Autoimmune diseases ... : - 10% SLE or ... classification #rheumatology
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