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differential classification cardiology treatment abscess agglutinin anemia antibodies antinuclear bronchiectasis cold conditions cryofibrinogenemia cryoglobulinemia cvid erythematosus extrarticular hemolytic hemoptysis hodgkins
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• They can cause ... Cause Organ Damage ... : • Clinical triad ... • Autoimmune diseases ... classification #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... lung disease (GLILD ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... , SLE • Pulmonary ... Vasculitis (e.g. ... #differential #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
often causes arthritis ... to exclude are infections ... , and SLE) • Urinalysis ... Serologies for Cryoglobulins ... #rheumatology #
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... / Autoimmune: ANCA-Assoc ... vasculitis (GPA ... Goodpasture's, SLE ... #pulmonary #causes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... salivary ducts Clinical ... MALT Lymphoma • Lung ... #Rheumatology # ... Diagnosis #Management
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... likely it will be clinically ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... Kidney disease common ... #Rheumatology
Bronchiectasis - Permanent dilation of an airway WHAT CAN YOU SEE ON CT? 1) Lack of tapering of
ON CT? ... ) WHAT ARE COMMON ... /Autoimmune diseae ... Bronchiectasis #pulmonary ... #diagnosis #differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
, vasculitis, sepsis ... Malignancy • Infections ... • Negative causes ... #rheumatology # ... hematology
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