9 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Rheumatic Diseases ... • Rheumatic Diseases ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Diseases: • Homogeneous ... tissue disease ... lupus erythematosus ... #patterns #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... findings (ANA, ... Serositis Labs: • ANA ... #Systemic #Lupus ... #Diagnosis #Rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
and Systemic lupus ... Association with disease ... with auto-immune diseases ... #diagnosis #rheumatology ... #table #ANA
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Interstitial lung ... , SLEPulmonary ... Antiphospholipid-antibody ... #differential #diagnosis ... #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
disease, and ocular ... : Systemic rheumatic ... diseases, such ... as systemic lupus ... LFT • ESR • ANA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Diseases • Septic ... lupus erythematosus ... (SLE) - Antinuclear ... antibody (ANA) ... #Disease #Rheumatoid
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
: • Clinical triad ... • Autoimmune diseases ... DDX: • ANCA (Antineutrophil ... lupus erythematosus ... (SLE), rheumatoid
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
: • Systemic rheumatic ... diseases, such ... disease, drug reactions ... most important diseases ... disease, and ocular