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lupus management antibodies antinuclear arthritis classification conditions extrarticular myositis pain patterns prs ra rheumatoid sjogrens treatment vasculitides
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Positive ANA ≠ Autoimmune ... Syndrome (SS), ... Arthritis, Sjögren Syndrome ... , Interstitial Pulmonary ... #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... Diagnosis: Systemic ... differential #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Diagnosis: • ANCA-associated ... rheumatologic diseases ... syndrome Arthritis ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... disease (30%): ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Interstitial lung ... , SLE • Pulmonary ... syndrome - SLE ... syndrome, SLE, ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... Mucocutaneous lymph node syndrome ... • Behcet syndrome ... • Cogan syndrome ... #Differential #Diagnosis
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
and Symptoms • ... disease, Pleural ... disease, Airways ... Thrombocytosis, Felty's syndrome ... #Symptoms #diagnosis
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
ANCA vasculitis ... Renal Syndromes ... life-threatening diseases ... Inflammatory eye disease ... #Renal #Syndromes
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... multisystemic disease ... • Mikulicz syndrome ... enlargement Sjogren's Syndrome ... #Sjogrens #Syndrome
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
lung disease Malignancy ... -1 antibodies (ANA ... lung disease • ... lung disease • ... differential #diagnosis
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