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differential lupus conditions cryoglobulinemia cryoglobulins extrarticular laboratory management pain patterns ra sjogrens testing types workup
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... with different rheumatic ... Rheumatic Diseases ... • Rheumatic Diseases ... , Interstitial Pulmonary
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
• Rheumatic ... • Interstitial lung ... Rheumatic fever ... Vasculitis (e.g. ... stenosis - Rheumatic
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... - Signs and Symptoms ... vasculitis, Raynaud's ... #Rheumatoid #Arthritis ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... (Granulomatous disease ... : Systemic rheumatic ... diseases, such ... , and SLE) • Urinalysis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... pain (20%) Renal disease ... #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... respectively, having rheumatoid ... Elevated serum rheumatoid ... (SLE), rheumatoid ... vasculitis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... rheumatic diseases ... disease, drug reactions ... most important diseases ... disease, and ocular
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Diseases • Septic ... SLE) - Antinuclear ... exclude inflammatory disease ... connective-tissue disease ... #Disease #Rheumatoid
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
multisystemic disease ... associated with other diseases ... demyelinating disease ... ) • Cutaneous vasculitis ... Vasculitis: •
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