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differential antinuclear lupus symptoms antibody behcet cryoglobulinemia cryoglobulins igg4 patterns phenotypes prs related sjogrens tafro thrombocytopenia types workup
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
cases • Sjögren syndrome ... Vasculitis: • ... vasculitis - MPO ... #antibodies #diagnosis ... diseases
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease, and ocular ... Mucocutaneous lymph node syndrome ... : • Behçet Syndrome ... • Cogan Syndrome ... LFT • ESR • ANA
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Syndrome (SS), ... (SLE), Systemic ... Arthritis, Sjögren Syndrome ... , Interstitial Pulmonary ... #rheumatology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Butterfly rash, Vasculitis ... Demyelinating syndromes ... disease (30%): ... #systemic #erythematosus ... #diagnosis #rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Diagnosis: • Systemic ... Mucocutaneous lymph node syndrome ... disease, and ocular ... • Behcet syndrome ... • Cogan syndrome
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Hyperviscosity Syndrome ... Cryoglobulinemia Syndrome ... • Autoimmune diseases ... 20% Sjögren's syndrome ... DDX: • ANCA (Antineutrophil
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... • Mikulicz syndrome ... ) • Cutaneous vasculitis ... Vasculitis: • ... Diagnosis #Management
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
vasculitis (AAV ... Renal Syndromes ... life-threatening diseases ... #Renal #Syndromes ... #management #treatment
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... , small-vessel vasculitis ... panuveitis, retinal vasculitis ... MCC-small vessel vasculitis ... #diagnosis #management
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