12 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... , Interstitial Pulmonary ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
alopecia Differential ... Diagnosis: • ANCA-associated ... fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... #Diagnosis #Rheumatology
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... vasculitis (GPA ... Goodpasture's, SLE ... #Diagnosis #pulmonary ... #causes
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
often causes arthritis ... ) pattern: antibodies ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology #
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Interstitial lung ... , SLEPulmonary ... Vasculitis (e.g. ... #joint #pain #differential ... #diagnosis #rheumatology
Bronchiectasis - Permanent dilation of an airway
WHAT CAN YOU SEE ON CT?
1) Lack of tapering of
ON CT? ... Bacterial, TB, NTM, Fungal ... /Autoimmune diseae ... Bronchiectasis #pulmonary ... #diagnosis #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Hypocomplementemia • Can cause ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
but important causes ... Assays for antinuclear ... antibodies, rheumatoid ... Diseases Fellows ... #diagnosis #differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... confirm DAH, r/o infection ... Goodpasture's cause ... sparing of the lung ... • IF staining patterns
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... , such as SLE, atherosclerotic ... #Differential #Diagnosis ... #Rheumatology