13 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Lymphoproliferative Disorders, Infection ... , Interstitial Pulmonary ... #Antibodies #ANA ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
alopecia Differential ... Diagnosis: • ANCA-associated ... fibromyalgia) • Infections ... • Libman-Sacks endocarditis ... #Diagnosis #Rheumatology
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Bacterial or viral infection ... • Interstitial lung ... , SLEPulmonary ... Cardiomyopathies - Viral infection ... #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
to exclude are infections ... ) pattern: antibodies ... , and SLE) • Urinalysis ... differential #diagnosis ... #rheumatology #
Hemoptysis - Differential Diagnosis Framework
Massive Hemoptysis: >150-300 mL in 24h
Airway disease: 
 • Bronchitis, Bronchiectasis, Malignancy
in 24h Airway disease ... Parenchyma: • Infection ... vasculitis (GPA ... Goodpasture's, SLE ... #Diagnosis #pulmonary
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
Infection with ... special media) • Infection ... Assays for antinuclear ... Diseases Fellows ... diagnosis #differential
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... : • 10%-15% Pulmonary ... MALT Lymphoma • Lung ... Sjogrens #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... , recent viral infection ... #Differential #Diagnosis ... #Rheumatology
Bronchiectasis - Permanent dilation of an airway
WHAT CAN YOU SEE ON CT?
1) Lack of tapering of
ON CT? ... Immunodeficiency 3) Infection ... /Autoimmune diseae ... Bronchiectasis #pulmonary ... #diagnosis #differential
Pulmonary Renal Syndromes - OnePager Summary
Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
vasculitis (AAV ... EGPA) • Auto-antibodies ... Other tests: • CT ... confirm DAH, r/o infection ... sparing of the lung