10 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... : The ANA patterns ... SLE), Sjogren's ... #Antibodies #ANA ... #patterns #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Associated Rheumatic ... SLE), Sjogren's ... #Antibodies #ANA ... #patterns #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... • Sjögren syndrome ... Vasculitis: • ... Renal-limited vasculitis ... #antibodies #diagnosis
Aortitis - Differential Diagnosis Framework
Non-Infectious Aortitis:
 • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
Non-Infectious Aortitis: • Vasculitides ... ), ANCA associated ... vasculitis (rare ... ) • Rheumatic Diseases ... erythematosus (
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitis and Vasculitides ... Vasculitis: + MPO-ANCA ... ) pattern: antibodies ... , and SLE) • Urinalysis ... #rheumatology #
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
syndrome - type ... DDX: • ANCA (Antineutrophil ... • Vasculitis ... SLE), rheumatoid ... vasculitis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
vasculitis, rheumatoid ... • Mesenteric vasculitis ... inflammation Cutaneous Vasculitis ... • (-) ANA + (+ ... #Diagnosis #Rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
rheumatic diseases ... , such as SLE, atherosclerotic ... ischemia • Skin: Erythematous ... often causes arthritis ... #Rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... Syndrome Diagnosis ... ) • Cutaneous vasculitis ... : 2% Systemic Vasculitis ... #Syndrome #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
SLE) - Antinuclear ... , a negative ANA ... ACE level, CXR, ANCA ... multiple myeloma) • ANA ... #Disease #Rheumatoid