Bursitis diagnosis sle ultrasound clinical abdominal pulmonary appendicitis rheumatology syndrome disease antinuclear antibodies anca laboratory vasculitis lupus management

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ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
• Systemic lupus erythematosus
1. Anti-dsDNA

ANA (Antinuclear ... ) • Systemic lupus ... in drug-induced SLE ... #antibodies #diagnosis ... #rheumatology #

Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like

Antinuclear Antibodies ... likely it will be clinically ... : Lupus (SLE), Systemic ... , Interstitial Pulmonary ... #Antibodies #ANA

Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
•

- GI tract: abdominal ... such as systemic lupus ... ) pattern: antibodies ... , and SLE) • Urinalysis ... #rheumatology #

Antinuclear antibodies and Systemic lupus
Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can

Antinuclear antibodies ... is clinically suspected ... overlap syndromes ... erythematosus #diagnosis ... #rheumatology #

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

SLE (Systemic Lupus ... ) Suspect: Clinical ... and fever) and laboratory ... Clinical Features ... #Rheumatology

Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
• Young

pathognomonic laboratory ... (Clinical Dx). ... • Nonsurgical abdominal ... #diagnosis #management ... signs #symptoms #rheumatology

Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease

overlaps with RA, SLE ... ab • RF • Antinuclear ... salivary ducts Clinical ... #Rheumatology # ... Diagnosis #Management

Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of

joint • Systemic lupus ... ) - Antinuclear ... double-stranded DNA antibodies ... ACE level, CXR, ANCA ... and RF (if clinical

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