51 results
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
leading to an allergic ... Sensitization" to Allergen ... complex -> Allergen-antibody ... complexes bind ... #Immunology #pathophysiology
Allergic Reaction Classification
Type 1 reaction: Acute anaphylactic reaction
Type 2 reaction: Cytotoxic reaction
Type 3 reaction: Immune complex
Type
Allergic Reaction ... reaction: Immune complex ... delayed reaction #Allergic ... Classification #Types #allergy
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
antigen-surface complex ... antigen-surface complex ... against these complexes ... or the entire complex ... #Immunology #pathophysiology
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Antigen-Ab immune complexes ... Hypersensitivity #Allergy ... #Allergic #Reactions
Complete AV Canal Defect on Echocardiogram

Among pts with Pulmonary Arterial Hypertension, those with Eisenmenger syndrome have
Complete AV Canal ... Complete AV canal ... Ivan_Echocardio #CAVCD ... #Complete #AVCanal
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Lead aVR on EKG
Lead aVR can provide some unique insight into 5 different conditions:

 - Acute
AVRT in narrow complex ... aberrancy in wide complex ... #AVR #Utility #ALiEM
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... antibiody -> Immune Complex ... > Incr Immune Complex ... Vasculitis #HUV #Pathophysiology
Type III Hypersensitivity: Pathogenesis and clinical findings
Definition: Small antigen-antibody complexes (produced from normal immune response to
antigen-antibody complexes ... HypersensitivityReaction #Allergy ... #Immunology #pathophysiology
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
leading to an allergic ... antigen-surface complex ... leading to an allergic ... antibody-antigen complexes ... An allergic reaction
Mechanical Bowel Obstruction and Ileus - Pathogenesis and Clinical Findings
Ileus: Functional bowel "blockage", no peristalsis
Mechanical Obstruction:
of bowel lumen Complete ... Incomplete obstructions ... bowel-movements (suggests complete ... light-switch pain") with complete ... obstruction #sbo #ileus #pathophysiology