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diagnosis differential rheumatology cascade coagulation dermatology petechiae petechial rash anticoagulant anticoagulation apixaban causes clot cryofibrinogenemia dabigatran edoxaban followup gammopathy glomerulonephritis
Pathophysiology of Hypocomplementemic Urticarial Vasculitis C1q/anti-C1q antibiody -> Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Pathophysiology ... antibiody -> Immune Complex ... > Incr Immune Complex ... #HUV #Pathophysiology ... #Rheumatology
Suggested algorithm for follow-up of monoclonal gammopathy of undetermined significance (MGUS) Mayo Clinic Risk Stratification Model. CBC,
Suggested algorithm ... Stratification Model ... CBC, complete blood ... MGUS #Followup #algorithm ... diagnosis #management #hematology
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
three primary pathophysiologic ... immunofluorescence Immune Complex ... Glomerulonephritis #Vasculitis ... differential #diagnosis #algorithm ... #rheumatology
The coagulation cascade is shown, separated into different phases with their endogenous and pharmacological inhibitors shown.
TF complexes with ... FXa which itself complexes ... multicomponent complexes ... multicomponent complexes ... #hematology #pathophysiology
Petechial/Purpuric Rashes- THE ALGORITHMIC APPROACH These rashes can be especially challenging and are associated with devastating differential
Purpuric Rashes- THE ALGORITHMIC ... ; however, an algorithmic ... purpura occurs in vasculitic ... petechiae require complete ... #Diagnosis #Dermatology
Review of the Coagulation Cascade Traditional Model: • Parallel extrinsic and intrinsic pathways. Contemporary Model: • 4 key
Cascade Traditional Model ... Contemporary Model ... multicomponent complexes ... result in both models ... #hematology #pathophysiology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
70 years with a modest ... precipitation of a complex ... precipitating complex ... cold insoluble complex ... #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Differential Diagnosis Algorithm ... Infection - Vasculitis ... - Autoimmune Vasculitis ... Work Up: • Complete ... #Causes #dermatology
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