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diagnosis differential management oncology aptt causes coagulation deficiency dermatomyositis nutrition prolonged pt algorithm antimda5dm antinxp2 antinxp2dm apml b12 bleeding bruising
Von Willebrand Disease - Most common inherited bleeding disorder Clinical • Easy bruising •
Disease - Most common ... Laboratory • Normal ... type 2B) • Normal ... PT/INR • Normal ... Disease #Diagnosis #Hematology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
the face, or the anterior ... Mechanic's hands #AntiMDA5DM ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
deficiency in the common ... inhibitors to the common ... amyloidosis #Abnormal ... #differential #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
• Incidence: common ... More common in severe ... and coagulopathy common ... 500 mg QD until normal ... diagnosis #management #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... • Acute DIC ABNORMAL ... PT/ABNORMAL PTT ... defects in the common ... Differential #Diagnosis #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... inhibitors to the common ... Jcortesizaguirr #Abnormal ... #differential #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Common Variable ... cancers: Most common ... levels are within normal ... Immunotherapies #CVID #Common ... hypogammaglobulinemia #immunology #hematology
Etiologies of Folate Deficiency • Decreased dietary intake - uncommon in this era • Increased requirements
dietary intake - uncommon ... tissue stores with normal ... differential #diagnosis #hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
Better call hematology ... exogenous, EPO levels: normal ... workup, think about common ... Algorithm #workup #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
lymphoma (HL) is an uncommon ... supraclavicular node • Anterior ... products that define normal ... (NSHL) - (most common ... classification #hematology
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