24 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
the face, or the anterior ... CD4+ and CD8+ T cell ... #AntiMDA5 #Dermatomyositis ... #rheumatology # ... dermatology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
incompetent • CLL ... : • Most common ... antigen • Matute’s CLL ... between classical CLL ... workup #oncology #hematology
Common RBC Inclusions and Associations
 • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia
 • Heinz
Common RBC Inclusions ... Thalassemia, Sickle cell ... Bodies #diagnosis #hematology
Arthritis of the Hand - Arthritis Patterns

Osteoarthritis:
• Osteoarthritis of the hand usually involves the DIP and
and PIP joints commonly ... • MCP + PIP + Wrist ... Hemochromatosis • Wrist ... MCP + 2nd PIP + all ... hand #diagnosis #rheumatology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Lymphocytic Leukemia (CLL ... Overview: • Most common ... routine CBC (rnost common ... uw_IMresidency #CLL ... Leukemia #oncology #hematology
Causes of Bone/Joint Pain in Sickle Cell Disease
Vaso-occlusive pain:
 • Mechanism: ischemic pain
 • Can present
Pain in Sickle Cell ... • Most common ... Arthritis: • Common ... diagnosis #causes #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
polyangiitis (GPA) is common ... disease or more commonly ... syndrome • Giant cell ... Polyangiitis #GPA #dermatology ... rash #diagnosis #rheumatology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm
Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
symptoms not as common ... - T Cell ~10% ... - B-Cell ~90% ... For Cure, Most common ... pathophysiology #Hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
deficiency in the common ... pathway: FX, FV, Fll ... inhibitors to the common ... impaired production Fll ... #differential #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Incidence: common ... • Induce blast cell ... More common in severe ... and coagulopathy common ... diagnosis #management #hematology