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diagnosis management differential workup hepatology symptoms anesthesia anesthesiology intraoperative neurology syndrome algorithm treatment cirrhosis cns hypertension pbc rheumatology agammaglobulinemia amyotrophic
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary ... quadrant discomfort Signs ... autoimmune disease (e.g ... Elevated ALP 2. ... specific ANAs (e.g
Jaundice - Differential Diagnosis Algorithm Pre-Hepatic - Unconjugated Hyperbilirubinemia Increased Production • Hemolysis • Ineffective Erythropoiesis • Hematoma Decreased
Sepsis • Drugs (e.g ... on Ultrasound Biliary ... Cholangiocarcinoma • Primary ... Diagnosis #Algorithm #Causes ... #Hepatology #bilirubinemia
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... 65 years PBC Pathophysiology ... intralobular bile ducts causes ... failure PBC Signs ... diagnosis #workup #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
of information (e.g ... for alternative causes ... biliary cholangitis ... , Primary sclerosing ... vascular disorder (e.g
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
significant portal HTN Signs ... estrogen such as ... pregnancy • Primary ... biliary cirrhosis ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
function test, ANA (e.g ... not required in all ... unclear, or if a primary ... hematologic disorder ... #Workup #hematology
Intraoperative Cardiac Ischaemia - Guidelines for Crises in Anaesthesia If the patient is unconscious, signs of cardiac
is unconscious, signs ... cardiac ischaemia primarily ... 12-lead ECG machine ... CM5 continuous ECG ... Obtain a 12-lead ECG
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
considered to be caused ... altered colour e.g ... nipple-like mass e.g ... , the plateau. e.g ... supply by fluid, e.g
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... (e.g. cirrhosis ... dullness, puddle sign ... concentration (bowel or biliary
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