62 results
EKG in Acute Pulmonary Embolism
The sensitivity and specificity for EKG findings in acute PE are low.
EKG
specificity for EKG ... EKG is helpful in ... evaluating for other causes ... in relation to ECG ... cardionerds #EKG
Common sodium channel blockers which cause QRS widening.

Anticonvulsants: 
 - Carbamazepine 
Antidysrhythmics:  
 - Group
blockers which cause ... - Group IA and ... IV (Diltiazem and ... QRS #widening #ECG ... #EKG #Pharmacology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... Membrane defects (e.g ... differential #diagnosis #hematology
High Output Heart Failure - Pathophysiology and Differential Diagnosis
Obesity - Systemic Vasodilation, Vasoactive Adipokines
Arteriovenous Fistula -
Heart Failure - Pathophysiology ... and Differential ... - Congenital (e.g ... HHT), Acquired (e.g ... Diagnosis #cardiology #causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
and Platelet Disorders ... Differential Diagnosis and ... function test, ANA (e.g ... or if a primary hematologic ... #Workup #hematology
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Causes include : ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #differential #hematology
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL and ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology #
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... Study #diagnosis #hematology ... #pathophysiology ... #hematology #laboratory
How do you work up an ischemic CVA?
A) Initial Evaluation
 • ABCs
 • IV access, monitor
r/o hemorrhage and ... Evaluate underlying cause ... Cardioembolic: • ECG ... +/- TEE (high Afib ... v Holter (r/o Afib
Immune Reactions and Immunosuppressant Drugs

Glucocorticoids - Inhibition of cytokine synthesis, e.g., IL-1, IL-2
Muromonab-CD3 - Monoclonal antibody
Calcineurin
Immune Reactions and ... cytokine synthesis, e.g ... Immunosuppressant #Drugs #Pharmacology ... #Pathophysiology