14 results
Hydroxychloroquine Serum Measurement in SLE
 • Terminal elimination half-life = 40 days ([HCQI reflects long-term intake)
concentration: > 750ng/mL and ... • Special cases ... (e.g. renal failure ... Measurement #SLE #rheumatology ... #pharmacology #
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... WBC >100k, + lab signs ... unless worrisome EKG ... diagnosis #management #hematology
Ascites - Diagnostic Approach and Differential Diagnosis
The most common causes: cirrhosis, malignancy and heart failure. Approx
The most common causes ... more than one cause ... (e.g. cirrhosis ... dullness, puddle sign ... incisional). 3) Signs
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Disease, PRES Pathophysiology ... autoantibodies that will cause ... ischemia and/or ... Lumbar Puncture, EEG ... CNS #neurology #rheumatology
X-Linked Agammaglobulinemia: Pathogenesis and clinical findings
The epidemiology of this disease is 1/340,000 births and roughly double
Signs of immunodeficiency ... to produce all classes ... humoral immunity Signs ... bacterial infections (e.g ... Agammaglobulinemia #XLinked #pathophysiology
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
countries (11-24 cases ... survival is 93-95% Pathophysiology ... symptoms are not caused ... of diagnosis (e.g ... Diagnosis #Management #Signs
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
lateral sclerosis Pathophysiology ... - Causes progressive ... LMN signs in the ... Escorial criteria uses ... EMG: LMN Signs in
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... not be subtle e.g ... E.g. 80 yo ESR cutoff ... variably: On one hand ... GCA #Temporal #Signs
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... ECG is vital while ... the determined cause ... icu #clinical #pharmacology
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
associated with signs ... pruritus (e.g., ... honey-colored crusts ... Varies with site, (e.g ... ; pruritis #dermatology