22 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
and the aPTT are ... (e.g. heparin contamination ... inhibitory drugs (e.g ... specific inhibitor (e.g ... hematology #coagulation
Chest Pain - Diagnosis and Workup Algorithm

History and Exam
Acute life-threatening causes:
 • Acute myocardial infarction
 •
History and ... life-threatening causes ... Pneumothorax • Pulmonary ... : • EKG • Bedside ... LET, lipase, PT. aPTT
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... to one factor e.g ... e.g. heparin ... #differential #
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... function test, ANA (e.g ... #Workup #hematology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm
Cervical:
 - Anterior
     • Infection
Causes of Localized ... Lymphadenopathy - Differential ... • Infection (e.g ... Infection (Forearm/Hand ... #Hematology #Oncology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Increased Requirement (e.g ... • Rule out B12 and ... Deficiency - Abnormal ... #Hematology
Erythrocytosis - Polycythemia Differential Diagnosis Algorithm

Elevated Hemoglobin:
 • Males: Hb > 16.5 g/dL/HCT ≥ 49%
 •
Polycythemia - Acquired Causes ... Hypoxia-driven: Cardiac/pulmonary ... Paraneoplastic (e.g ... ), TEMPI (VEGF normal ... Diagnosis #Algorithm #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis and ... mixing study (aPTT ... mild cases) • ... hemophilia type (e.g ... Management #treatment #hematology
Hypoxia and Hypoxemia - Overview
Hypoxia - insufficient oxygen delivered to tissues to meet demands
Hypoxemia - low
stagnant hypoxia (e.g ... carrying capacity (e.g ... hemoglobin (e.g ... #differential # ... diagnosis #causes
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
performed PT, PTT ... decrease in most cases ... differential - ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology