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diagnosis causes coagulation differential abnormal algorithm disease nonalcoholic prolonged pt syndrome treatment activation aih autoimmune blood cirrhosis dic diet disorders
Non-alcoholic fatty liver disease algorithm. For those patients with NAFLD or liver disease of unknown aetiology,
patients with NAFLD ... or liver disease ... fibrosis; FIB-4 ... algorithm #Referral #Management ... #Hepatology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Nonspecific inhibitors e.g ... to one factor e.g ... inhibitory drugs e.g ... Nonspecific inhibitor e.g ... #differential #hematology
Mixing Study • Clotting tests can be abnormal due to either a clotting factor deficiency, or
factor activity (e.g ... clotting test (e.g ... PT and/or aPTT) ... Study #diagnosis #hematology ... #hematology #laboratory
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
and the aPTT are ... Pre-analytical cause (e.g ... inhibitory drugs (e.g ... specific inhibitor (e.g ... #differential #hematology
Non-Alcoholic Fatty Liver Disease (NAFLD) - Diagnosis Algorithm Low Suspicion: ≤ 1 feature of
Non-Alcoholic Fatty Liver ... Disease (NAFLD) ... cirrhosis AND ... FIB < 1.3 ... Diagnosis #Algorithm #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
cases: INR/PT, aPTT ... (liver disease, ... function test, ANA (e.g ... bypass), LFT (liver ... Causes #Workup #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis and ... established disease) • aPTT ... mixing study (aPTT ... hemophilia type (e.g ... #treatment #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
S Pathophysiology ... DIC • Severe Liver ... INR < 2.3 - APTT ... causes #treatment #management ... #hematology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
inflammation (eg ... been reported (eg ... of Hepatitis (eg ... Histology Findings (eg ... #Hepatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
underlying disease (eg ... • Infection (eg ... thrombocytopenia • Liver ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
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