15 results
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
von Willebrand Syndrome ... Lymphoproliferative disorders (e.g ... Myeloproliferative disorders (e.g ... Diagnosis #Management #treatment ... #hematology #differential
Mesenteric Ischemia - Differential Diagnostic Schema
Chronic: ASCVD, Venous, Vasculitides 5% (PAN, [E]GPA, IgA, MPA)
Acute
 - Venous
Mesenteric Ischemia - Differential ... Vasculitides 5% (PAN ... inflammation (e.g ... Antiphospholipid syndrome ... hypovolemia), Meds/Treatments
Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
all extremity, facial ... Hands or feet • Pain ... Electrodiagnostic studies - EMG ... Treatment: • Plasmapheresis ... diagnosis #management #treatment
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
lesions + Rheumatic pain ... thickening • Osteitis: pain ... , parts of the axial ... and lower jaw Treatment ... antiinflammatory properties e.g
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... disease, Vasculitis (e.g ... conditions #joint #pain ... #differential # ... diagnosis #rheumatology
Palpitations - Differential Diagnosis Framework

What?
• It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... exam • 12-lead ECG ... Valvular disease (e.g ... Symptoms: • Chest pain ... /Afib/WPW) • Loss
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
thyroid, Sjogren syndrome ... “dropping head syndrome ... life-threatening Differential ... - Brain stem/Cranial ... Serologic and EMG
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
• Fever is the main ... underlying disease (eg ... • Infection (eg ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... initiation • Differential ... diagnosis #management #hematology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
not be subtle e.g ... very remarkable w/differential ... E.g. 80 yo ESR cutoff ... claudication: pain ... Treatment of GCA