10 results
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... eosinophilia (common causes ... glucocorticoid treatment ... signs or symptoms (eg ... Differential #diagnosis #hematology
Achalasia Summary

Epidemiology: 10 cases per 100,000 individuals

Defined by inadequate relaxation of the LES and aperistalsis
Primary or
pseudoachalasia: • Short ... Weight loss (>6.8 kg ... Treatment options ... fibers of the LES (eg ... LES pressure (eg
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... organ damage • Treatment ... Low calcium • Treatment ... unless worrisome EKG ... diagnosis #management #hematology
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... hemophilia type (e.g ... Classify severity Treatment ... by a hemophilia treatment ... #hematology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
anterior chest wall, parts ... Rule out other causes ... and lower jaw Treatment ... antiinflammatory properties e.g ... diagnosis #management #Dermatology
Ventricular Fibrillation on POCUS Echocardiogram - Parasternal Short Axis

50's male witnessed arrest. Unknown hx. AED no
Fibrillation on POCUS Echocardiogram ... - Parasternal Short ... Fine Vfib can be ... getting 12 lead ECG ... #PSAX #POCUS #Echocardiogram
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
• Thrombosis (e.g ... ET-associated mutation (e.g ... thrombocytosis (e.g ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology
Causes of Neutropenia - Differential Diagnosis
Neonate:
 - Infection - by far the most common cause
 -
Causes of Neutropenia ... the most common cause ... hypertension and/or drug treatment ... Constitutional disorders, eg ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)

High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
▪ Infections (e.g ... pro-inflammatory cytokines (e.g ... Immunosuppression (e.g ... anti-IFN-γ antibodies (e.g ... Diagnosis #Management #Hematology
Pyoderma Gangrenosum (PG)
50 M Crohn’s dz had a small pustule on the ankle 4 mo ago
medications in most cases ... corticosteroid (eg ... PG secondary treatment ... clinical #photo #dermatology