15 results
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
Complement: IgA nephropathy ... involvement: Anti-GBM Disease ... Glomerulonephritis #Vasculitis #differential ... #diagnosis #algorithm ... #rheumatology
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
Optic Neuritis - ... Moderate orbital pain ... other auto-immune diseases ... #treatment #rheumatology ... #ophthalmology
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
Leg Pain - Differential ... Diagnosis Framework ... : • Neuropathy ... #differential # ... #extremity #msk
Common causes of Acute Kidney Injury AKI - Differential Diagnosis
HEMODYNAMIC
 • Cardiac failure: Impaired forward flow,
Kidney Injury AKI - Differential ... Diagnosis HEMODYNAMIC ... • Primary GNs: Disease ... IgA nephropathy ... (AIN) • Drugs
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint Pain ... Ischemic optic neuritis ... • Peripheral neuropathy ... #differential # ... diagnosis #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Arthritis: • Joint pain ... meningitis • Cranial neuritis ... • Peripheral neuropathy ... #Rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
- Arthritis Differential ... Diagnosis Framework ... #Differential # ... Diagnosis #MSK # ... rheumatology #Monoarticular
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... Diagnosis Framework ... Differential ... , testes -> pain ... #diagnosis #rheumatology
Blurry Vision - Differential Diagnosis Framework

Anatomical Approach to Eye Disease:
1. Lids/Lashes
2. Extraocular Muscles/Motility
3. Conjunctiva/Sclera
4. Cornea
5. Anterior
Approach to Eye Disease ... Inflammation • Optic neuritis ... hereditary optic neuropathy ... vision • Eye pain ... #diagnosis #ophthalmology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
Symptoms of Joint Disease ... categories of joint disease ... #MSK #rheumatology ... approach #workup #differential ... #diagnosis #arthritis