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management diagnosis hivaids opportunistic prevention differential syndrome disease oncology algorithm hemophagocytic lymphohistiocytosis causes table anemia cdiff clostridium hemeonc lupus medications
IDSA Aspergillosis Treatment • Invasive pulmonary aspergillosis (IPA) • CNS aspergillosis • Cardiac Aspergillus infection •
IDSA Aspergillosis ... Treatment • Invasive ... Aspergillosis #Treatment ... #management #pharmacology ... #IDSA
Proposed Treatment Algorithm for MAS / HLH #MAS #HLH #Hemophagocytic #Lymphohistiocytosis #Management #Treatment #Algorithm #Hematology
Proposed Treatment ... Algorithm for MAS / HLH ... #MAS #HLH #Hemophagocytic ... Lymphohistiocytosis #Management #Treatment ... #Algorithm #Hematology
IDSA Recommendations for the Treatment of Clostridium difficile Infection in Adults Source: https://doi.org/10.1093/cid/cix1085 #Management #Clostridium #CDifficile #IDSA2017 #Guidelines
IDSA Recommendations ... for the Treatment ... Clostridium difficile Infection ... doi.org/10.1093/cid
IDSA Treatment of Necrotizing Infections of the Skin, Fascia, and Muscle • Mixed infections • Streptococcus
IDSA Treatment of ... Necrotizing Infections ... fasciitis #Skin #IDSA ... #Treatment #management ... #antibiotics #pharmacology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... : • Infections ... Unknown cause Treatment ... diagnosis #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
can mimic common infections ... • Bicytopenia Treatment ... : • Infection ... diagnosis #management #treatment ... #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... • Nonmalignant hematologic ... Rebound effect from treatment ... : Chronic infections ... Diagnosis #Algorithm #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
erythematosus • HLH ... deficiency Infections ... Differential #Diagnosis #Hematology
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelofibrosis Infectious ... Non malignant hematologic ... effect following treatment ... states • Non-hematologic ... Algorithm #Causes #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
lymphohistiocytosis (HLH ... SLE], AOSD) • Infection ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
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