12 results
Hypothyroid Myopathy
Very common (up to 80% ) in patients with hypothyroidism
Pathophysiology:
 • T4 deficiency leads to
patients with hypothyroidism ... which impairs musde ... Asymptomatic CK ... pathophysiology #signs #symptoms ... #endocrinology
Hypothyroidism and Hyperthyroidism - Symptoms and Signs
Hypothyroidism:
 - General - From asymptomatic to myxedema coma, “Like
- Symptoms and ... cold, pale - Muscles ... Amy Chung, MD, MSc ... #Hyperthyroid #Symptoms ... Signs #Diagnosis #endocrinology
Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
Causes of Elevated CK ... Levels Acute CK ... ): • PROXIMAL MUSCLE ... Endocrine: Hypo/hyperthyroidism ... myopathy - Autoimmune
Hyperthyroidism – symptoms and signs. 

Symptoms:

Weight loss, Increased appetite, Irritability/behaviour change, Restlessness, Malaise, Stiffness, Muscle weakness,
Hyperthyroidism ... Malaise, Stiffness, Muscle ... myopathy, Proximal muscle ... Pretibial myxoedema #Hyperthyroidism ... #Diagnosis #Endocrinology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... less systemic symptoms ... @AnnKumfer #Autoimmune
Myoedema in Hypothyroidism on Physical Exam

Hypothyroidism is a clinical syndrome resulting from the production, secretion or
Myoedema in Hypothyroidism ... varied clinical symptoms ... There are several symptoms ... characterized by muscle ... video #neurology #endocrinology
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Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
Hypothyroidism – ... symptoms and signs ... Symptoms: Tiredness ... , Myalgia, Muscle ... #PhysicalExam #Endocrinology
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Common Causes: • Autoimmune ... pseudomonas) Autoimmune ... develop another autoimmune ... disorder - Primary hypothyroidism ... addisons #disease #endocrinology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Endocrine: Hypo/Hyperthyroidism ... - Autoimmune: ... : • Triad of symptoms ... : - Muscle pain ... urine • Other symptoms
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... Very high serum CK