12 results
diagnosis differential rheumatology management myopathy signs erythematosus hypothyroid lupus neurology pathophysiology sle systemic treatment adrenal cns complications creatine demyelinating diseases
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... associated with higher CK ... greater level of muscle ... less systemic symptoms ... @AnnKumfer #Autoimmune
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Weakness, Normal CK ... - Myositis ... Weakness, Incr CK ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Causes of Elevated CK ... Levels Acute CK ... ): • PROXIMAL MUSCLE ... myopathy - Autoimmune ... Inclusion body myositis
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... symptoms: weeks ... • Myalgia • Myositis ... inclusion body myositis ... Diagnosis: • CK
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
which impairs musde ... Asymptomatic CK ... proximal myopathy → Muscle ... pathophysiology #signs #symptoms ... #endocrinology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... Very high serum CK
Multiple Sclerosis - Summary Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
) is an autoimmune-mediated ... neuritis • Partial myelitis ... defect SIGNS/SYMPTOMS ... Signs and symptoms ... /or cerebellar symptoms
Hypothyroidism and Hyperthyroidism - Symptoms and Signs Hypothyroidism: - General - From asymptomatic to myxedema coma, “Like
Hyperthyroidism - Symptoms ... cold, pale - Muscles ... Amy Chung, MD, MSc ... #Hyperthyroid #Symptoms ... Signs #Diagnosis #endocrinology
Adrenal Insufficiency - Diagnosis and Management Summary Primary Adrenal Insufficiency: Most Common Cause in the US: Autoimmune Adrenalitis Other
Cause in the US: Autoimmune ... ketoconazole, etomidate) Symptoms ... N/V (60-90%), Muscle ... Diagnosis #Management #Endocrinology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Joints: myalgia and muscle ... Conjunctivitis, mucositis ... Presentation - Systemic Symptoms ... #rheumatology #classification
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