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diagnosis differential erythematosus lupus neurology rheumatology systemic complications cord creatine elevated fractures fragility kinase management musculoskeletal myelitis orthopedics pathologic pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
Erythematosus (SLE ... - Myositis ... Myopathy (Also caused ... #MSK #Musculoskeletal ... pathophysiology #signs #symptoms
Creatine Kinase - Causes of Elevated CK Levels Acute CK Elevation (Pain > Weakness): • RHABDOMYOLYSIS
Creatine Kinase - Causes ... ): • PROXIMAL MUSCLE ... Neuromuscular disorders ... , SLE • PROXIMAL ... Inclusion body myositis
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
Spinal Cord Disorders ... Non-compressive Spinal Cord Causes ... - Transverse myelitis ... Behcet disease - SLE ... differential #algorithm
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Focal inflammatory disorder ... Bilateral signs and/or symptoms ... Evaluate for NMO, SLE ... • Infectious causes ... : - SLE - Neurosarcoidosis
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
Tumours - See ... Pain/Proximal Muscle ... • Bone Marrow Disorder ... Fractures #Pathologic #MSK ... #Orthopedics #Causes
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... erythematosus (SCLE ... ) • Endocrine disorders ... • Transverse Myelitis ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... Joints: myalgia and muscle ... Presentation - Systemic Symptoms ... vasculitis, and SLE ... #rheumatology #classification
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