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diagnosis differential neurology autoimmune complications cord disorders erythematosus lupus musculoskeletal myelitis pathophysiology rheumatology sams signs sle spinal spinalcord statin systemic
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations • Immune Complex Deposition - Arthralgia, Arthritis
- Myositis ... femoral heads • Myopathy ... (Also caused by ... Erythematosus #SLE #MSK ... pathophysiology #signs #symptoms
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... • Myalgia • Myositis ... inclusion body myositis ... Diagnosis: • CK ... #diagnosis #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure CK ... (symmetric) • CK ... weakness • CK ... statins - probably caused
Spinal Cord Disorders - Differential Diagnosis Framework Spinal cord neurological lesion: Clinical findings: • Symptoms and signs below
findings: • Symptoms ... Non-compressive Spinal Cord Causes ... - Transverse myelitis ... - Radiation myelopathy ... differential #algorithm
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
10-33% develop MS ... the spinal cord (Myelopathy ... Bilateral signs and/or symptoms ... • Infectious causes ... #diagnosis #management
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