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differential myopathy signs autoimmune myositis pathophysiology adrenal approach arthritis classification cushing disorders features hematology hyperfunction hyperthyroid hyperthyroidism hypothyroidism joint lymphomas
Hypothyroid Myopathy Very common (up to 80% ) in patients with hypothyroidism Pathophysiology: • T4 deficiency leads to
Hypothyroid Myopathy ... Asymptomatic CK ... Rhabdomyolysis (rare) #Hypothyroid ... pathophysiology #signs #symptoms ... #endocrinology
Hypothyroidism – symptoms and signs. Symptoms: Tiredness/malaise, Weight gain, Anorexia, Cold intolerance, Poor memory, Change in appearance, Depression, Poor libido,
Symptoms: Tiredness ... , Myalgia, Muscle ... reflexes, Anaemia #Hypothyroid ... #Diagnosis #PhysicalExam ... #Endocrinology
Hypothyroidism and Hyperthyroidism - Symptoms and Signs Hypothyroidism: - General - From asymptomatic to myxedema coma, “Like
Hyperthyroidism - Symptoms ... cold, pale - Muscles ... #Hyperthyroid # ... Symptoms #Signs ... #Diagnosis #endocrinology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Symptoms (SAMS) ... toxic myopathy, hypothyroid-induced ... Atorvastatin Diagnosis ... : • CK: - SAMS ... toxicity #myopathy #diagnosis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
associated with higher CK ... greater level of muscle ... less systemic symptoms ... /full triad at diagnosis ... #rheumatology
Cushing Syndrome Testing Algorithm INDICATIONS FOR TESTING: • Suspected Cushing syndrome (central obesity, muscle weakness, refractory hypertension) Testing:
Syndrome Testing Algorithm ... central obesity, muscle ... Urine Free by LC-MS ... Cushing #Syndrome #diagnosis ... #algorithm #endocrinology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... myopathies Diagnostic ... RP-ILD), dermato-rheumatologic ... Myositis #Myopathy #rheumatology ... #differential #diagnosis
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... pattern of spread, B symptoms ... Amy Chung, MD, MSc ... #Diagnosis #NonHodgkin
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Ligament • Bone • Muscle ... or nerve root Symptoms ... #Joint #Pain #MSK ... #rheumatology # ... #differential #diagnosis
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