31 results
diagnosis hematology differential algorithm causes hemolysis management leukemia atlas chronic clinical extravascular hodgkins intravascular lymphocytic lymphoma microscopy monoclonal morphology agglutinin
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Burr Cell RBC (Echinocyte ... Bite Cell RBC: G6PD ... Target Cell RBC ... differential #diagnosis #hematology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Increased red cell ... Increased red cell ... #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... RBC) Morphology ... spherocytosis, Hemolytic ... - Sickle cell anemia ... #differential #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
anemia): ... ) (e.g. lupus, CLL ... • Intrinsic RBC ... Hemoglobinopathies (e.g. sickle cell ... differential #diagnosis #hematology
Common RBC Inclusions and Associations • Howell Jolly Bodies: Hyposplenism, Asplenism, Severe hemolytic anemia • Heinz
Common RBC Inclusions ... , Hemolytic anemia ... : Hemoglobin H disease ... Thalassemia, Sickle cell ... Bodies #diagnosis #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle cells ... Consider sickle cell ... Diagnosis #Algorithm #workup ... #hematology #testing
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoid malignancy (CLL ... malignancies - B-cell ... malignancies -> CLL ... #hemolytic #anemia ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Physical Exam/Signs ... can indicate disease ... • Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Microangiopathic hemolytic ... Microspherocytes: Autoimmune hemolytic ... red cells: Sickle ... cell disease Bite ... Smear #Analysis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... , Drugs, Liver Disease ... Defects: Sickle cell ... anemia, Thalassemias ... Differential #Diagnosis #hematology
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