17 results
Acute and Chronic Causes of Dyspnea - Differential Diagnosis
Pulmonary/Chest Wall:
 • Acute: Trauma, COPD exacerbation, Asthma
Acute: Trauma, COPD ... : Asthma, COPD, ... : Anemia, Arrhythmia ... hernia, Obesity CNS ... : ALS, Glycogen
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... : CNS manifestations ... - infiltrates (anemia ... #Oncology #Diagnosis
Hypoxemia / Hypoxia - Rapid Response Management Algorithm

Stridor - Upper airway pathology:
 • Anaphylaxis
 • Foreign
Rapid Response Management ... asthma • Pleural disease ... Hypoventilation: • CNS ... e.g., GBS, MG, ALS ... differential #Diagnosis #Management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Scleromyxedema (CNS ... (-) hemolytic anemia ... due to cold IgG ... Differential #Diagnosis #Oncology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome ... (CAS): - Due ... • Symptoms of anemia ... hemolysis • C3↓ C4 ... #hematology #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... meningitis), MCC CNS ... Recurrent and chronic ... collaboration • CNS ... #diagnosis #management
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... low Ca - q8 h TLS ... replacement Cord ... ) - Symptoms: CNS ... ) - Symptoms: CNS
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... with leukopenia, anemia ... tests ↑ AST ↑ ALT ... #Diagnosis #Management ... #Hematology #Rheumatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cells can indicate disease ... • Neutropenia, anemia ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... 5) Symptoms of anemia ... chemotherapy for low-risk disease ... #Leukemia #oncology ... #diagnosis #management