11 results
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Asthma - COPD ... Hepatopulmonary syndrome ... Guillain Barre - ALS ... Transverse myelitis • Hematology ... : - Anemia
Acute and Chronic Causes of Dyspnea - Differential Diagnosis
Pulmonary/Chest Wall:
 • Acute: Trauma, COPD exacerbation, Asthma
Chronic Causes of Dyspnea ... Tamponade • Chronic: Anemia ... hernia, Obesity CNS ... Encephalitis • Chronic: ALS ... BostonChiefs #Dyspnea
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... involvement • 30%: CNS ... : CNS manifestations ... - infiltrates (anemia ... • Bone pain, dyspnea
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Agglutinin Syndrome ... (CAS): - Due ... fatigue, pallor, dyspnea ... hemolysis • C3↓ C4 ... #hematology #diagnosis
Hypoxemia / Hypoxia - Rapid Response Management Algorithm

Stridor - Upper airway pathology:
 • Anaphylaxis
 • Foreign
Rapid Response Management ... asthma • Pleural disease ... Hypoventilation: • CNS ... e.g., GBS, MG, ALS ... differential #Diagnosis #Management
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Lymphoma (HCV) • CLL ... Scleromyxedema (CNS ... (-) hemolytic anemia ... due to cold IgG ... Differential #Diagnosis #Oncology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... low Ca - q8 h TLS ... Facial swelling, dyspnea ... ) - Symptoms: CNS ... ) - Symptoms: CNS
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... meningitis), MCC CNS ... collaboration • CNS ... #diagnosis #management ... signs #symptoms #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
nervous system (CNS ... with leukopenia, anemia ... tests ↑ AST ↑ ALT ... #Diagnosis #Management ... #Hematology #Rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... • Cough • Dyspnea ... Weight loss • Anemia ... number of sites of disease ... #oncology #management