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Pulmonary Renal Syndrome: Investigations and Management

#Pulmonary #Renal #Syndrome #Diagnosis #Workup #Management
Pulmonary Renal ... Syndrome: Investigations ... and Management ... #Pulmonary #Renal ... #Syndrome #Diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Pulmonary Renal ... Syndrome Definition ... Differential Diagnosis ... anti-GBM ab, ANA, C3, C4 ... #differential #diagnosis
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
Differential diagnoses ... for the neuro-ophthalmologic ... Miller-Fisher syndrome ... #Differential #Diagnosis ... #Causes #Ophthalmology
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
Nerve Palsy • CN ... Nerve palsy • CN ... One-and-a-half Syndrome ... #Localization #ophthalmology ... #differential #diagnosis
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Manifestations of Serotonin Syndrome ... • Ophthalmologic ... Diaphresis, flushing • CNS ... ucsdim #Serotonin #Syndrome ... spectrum #signs #diagnosis
Anisocoria Evaluation Flow Chart - Differential Diagnosis
1. Check pupillary reaction to light 
2. Measure pupil size.
- Differential Diagnosis ... - Horner's Syndrome ... Anisocoria - CN ... #Differential #Diagnosis ... #Ophthalmology
Adie's Pupil
What? Unknown nature & benign
 • Regular and mildly dilated pupil (4-6mm);
 • Light-near dissociaton;
Holmes-Adie Syndrome ... females Differential Diagnosis ... : • CN Ill Palsy ... #Adies #Pupil #PhysicalExam ... #neurology #ophthalmology
Approach to the A-a Gradient
A-a gradient = PAO2 - PaO2
A-a gradient = [FiO2 x (Patm -
Hypoventilation: CNS ... Hypoventilation Syndrome ... Intracardiac, Pulmonary ... Hepatopulmonary Syndrome ... #differential #diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
basal ganglia, CNS ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... inhibitors • Uveitis- Ophthalmology ... #diagnosis #management
Pupillary Abnormalities  Overview
 - Unequal Pupils (anisocoria)
 - Tonic pupil (Adie's pupil)
 - OculomotorNerve (CN
OculomotorNerve (CN ... - Homer's Syndrome ... #Diagnosis #Ophthalmology