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management diagnosis differential syndrome fungal idsa infectiousdiseases invasive renal abscess aspergillosis aspergillus brain capillary capsulatum clarksons clinical crypto cryptococcal diuresis
IDSA Aspergillosis Treatment • Invasive pulmonary aspergillosis (IPA) • CNS aspergillosis • Cardiac Aspergillus infection •
Aspergillosis Treatment ... • Invasive pulmonary ... aspergillosis (IPA) • CNS ... Diseases Fellows ... #management #pharmacology
Invasive Aspergillus (IA) - Diagnosis and Management Aspergillus is ubiquitous in nature. Most invasive infections are caused
are caused by members ... presentations: • Pulmonary ... Rhinosinusitis, CNS ... this morphology Treatment ... Diseases Fellows
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... extrapulmonary disease ... or meningitic disease ... especially the CNS ... MC: CNS CSF: •
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... shows a small, stable ... Lung #Abscess #pulmonary ... #differential #causes
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
life-threatening diseases ... Inflammatory eye disease ... confirm DAH, r/o infection ... Goodpasture's cause ... diagnosis #management #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... : • 10%-15% Pulmonary ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... Sjogrens #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
to exclude are infections ... tract, and often causes ... , recent viral infection ... chorioretinitis, CNS ... Differential #Diagnosis #Rheumatology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... filling +++ (risk of pulmonary ... of infections) ... spacing of IVIg cures ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
(depending on CNS ... associated with infection ... or autoimmune disease ... for refractory disease ... #management #hematology
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS What Is IRIS? • A state of hyperinflammatory response that
worsening of that disease ... Lymphadenitis, pulmonary ... pleural effusions, CNS ... pericarditis, peritoneal disease ... lymphadenitis, pulmonary
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