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diagnosis treatment arthritis differential symptoms erythematosus gout hemophagocytic hlh lupus lymphohistiocytosis msk rheumatoid sle systemic vasculitis activation antinxp2 antinxp2dm autoimmune
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Tunnel, Sicca Syndrome ... Scleritis, Heart Disease ... (RA + Neutropenia ... #diagnosis #rheumatology ... #signs #symptoms
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
basal ganglia, CNS ... meningitis), MCC CNS ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation Syndrome ... highly inflammatory disease ... nervous system (CNS ... #Diagnosis #Management ... #Hematology #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Demyelinating Syndrome ... Cerebrovascular Disease ... #neurology #rheumatology ... cerebritis #diagnosis #management
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... Thrombocytosis, Felty's syndrome ... Rheumatoid #Arthritis #RA ... #Signs #Symptoms ... #diagnosis #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Demyelinating syndromes ... pain (20%) Renal disease ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA ... • 8%-27% for CNS ... Nephrogenic DI Hematologic ... #Rheumatology # ... Diagnosis #Management
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... mass and NO prior signs ... Inflammatory Arthritides (RA ... diffuse chondral disease ... diagnosis #msk #rheumatology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... WBC >100k, + lab signs ... TLS #diagnosis #management ... #hematology
Optic Neuritis - Diagnosis and Management • Epidemiology: Female (75%), 18-50 years, caucasian • Symptoms: Moderate visual
Diagnosis and Management ... Unilateral • Signs ... other auto-immune diseases ... Neuritis #Diagnosis #Management ... #treatment #rheumatology
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