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antibodies differential erythematosus lupus systemic ana antinuclear associations autoantibodies clinical msas neurology patterns signs specific symptoms syndrome tafro thrombocytopenia transverse
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Inclusion Body Myositis ... MithuRheum #Myositis ... #rheumatology # ... table
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... Anticoagulant (LAC) • Sjogren ... Peptide (CCP) • Myositis ... #diagnosis #associations ... #table
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Systemic Lupus (SLE ... loss (50%) Eye: Sjögrens ... Glomerulonephritis Myositis ... signs #symptoms #diagnosis ... #rheumatology
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... of Transverse Myelitis ... that results in CNS ... Transverse Myelitis ... #diagnosis #management
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
erythematosus (SLE ... ), Sjogren's Syndrome ... Syndrome, Myositis ... ANA #patterns #rheumatology ... #diagnosis #differential
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... overlaps with RA, SLE ... neuropathy, transverse myelitis ... #Syndrome #Rheumatology ... #Diagnosis #Management
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... dermatomyositis, Sjogren ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
erythematosus (SLE ... ), Sjögren’s syndrome ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
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