8 results
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Anti-Synthetase Syndrome ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Aseptic necrosis of hip ... Demyelinating syndromes ... signs #symptoms #diagnosis ... #rheumatology
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... salivary ducts Clinical ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... #Rheumatology #
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Clinical Features ... and CNS • Headache ... • Transverse Myelitis ... #Rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Cold Agglutinin Syndrome ... (CAS): - Due ... Viral Infection Clinical ... Mycoplasma, EBV, HIV ... hemolytic #anemia #hematology
Ober's Test for TFL/ITB Inflammation

With the patient in the lateral position, affected side up.  The
leg towards the table ... (hip adduction) ... Iliotibial #Band #Syndrome ... #knee #clinical ... #video #physicalexam
Autoimmune Myositis - Differential Diagnosis Framework

Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential Diagnosis ... RP-ILD), dermato-rheumatologic ... weakness + atrophy- Hip ... nucleotidase 1A (Anti cN ... #Myopathy #rheumatology
Trigger Finger - Stenosing flexor tendon tenosynovitis

There is a change in the slip between the tendon
one shown in the video ... The diagnosis is ... clinical, and can ... #physicalexam # ... orthopedics #rheumatology