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management neurology differential rheumatology signs symptoms video causes myositis nephrology ophthalmology algorithm autoimmune barre erythematosus gbs guillain hand lupus msk
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Diagnosis Framework ... pulmonary etc) • CNS ... • Acute stroke syndromes ... Paraneoplastic syndrome ... #Differential #Diagnosis
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
level of muscle weakness ... anti-synthetase syndrome ... /full triad at diagnosis ... have significant weakness ... after 2 years of treatment
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... Other brainstem syndromes ... • Transverse myelitis ... pain • Extra-CNS ... Manifestations #diagnosis
Causes of Neuromuscular Weakness • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Neuromuscular Weakness ... Tetanus, Transverse Myelitis ... Guillain-Barre syndrome ... heavy metals), Critical ... #differential #diagnosis
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Myositis Specific ... Anti-Synthetase Syndrome ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology ... #table
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... - Clinical Presentation ... Weakness: - Weakness ... Diagnosis: • ... Treatment: •
Guillain-Barre Syndrome - Summary Acute AIDP that presents with rapidly progressive flaccid weakness Epidemiology: • 1-2 cases/100,000 per
meningococcal, H1N1) Clinical ... Guillain-Barre Clinical ... Guillain-Barre Diagnosis ... #diagnosis #management ... #treatment #neurology
Statin Induced Muscle Toxicity - Summary Clinical Presentation: • Elevations of serum creatine kinase with proximal myalgia
Toxicity - Summary Clinical ... proximal myalgia and weakness ... symmetric muscle weakness ... Atorvastatin Diagnosis ... IU/I • SAMS clinical
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Clinical Picture ... Limb- proximal weakness ... myasthenia Diagnosis ... Clinical DX: - ... Myasthenia #Gravis #diagnosis
Bell's Palsy - Diagnosis and Management Summary - GrepMed Handbook Acute Idiopathic Unilateral Facial Nerve (CN7) Palsy Presentation:
Bell's Palsy - Diagnosis ... AND lower facial weakness ... - Atypical Clinical ... sarcoid or other CNS ... #Management #Treatment
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