11 results
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
- Differential Diagnosis ... Sciatica • Tarsal tunnel ... • Myositis/pyomyositis ... #lower #extremity ... #msk #physicalexam
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Causes of Neuromuscular ... Demyelinating Disease (MS ... Tetanus, Transverse Myelitis ... Guillain-Barre syndrome ... #differential #diagnosis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... of Transverse Myelitis ... that results in CNS ... Transverse Myelitis ... • Infectious causes
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
Differential diagnoses ... Carcinomatosis Vascular ... Miller-Fisher syndrome ... pseudotumor • Orbital myositis ... #Causes #Ophthalmology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
(CES) is usually ... - Emergency Causes ... • Transverse myelitis ... lumbar stenosis • Vascular ... #causes #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... Non-compressive Spinal Cord Causes ... - Transverse myelitis ... Vascular/Blockage ... MCTD, Sjogren syndrome
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Diagnosis: • Dry ... Hypocomplementemia • Can cause ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... phenomenon (16%) MSK
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... (hypertension, lower ... and CNS • Headache ... • Transverse Myelitis ... Erythematosus #Diagnosis
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
pulse deficits vascular ... the upper and lower ... tract, and often causes ... Palpable purpura (lower ... chorioretinitis, CNS
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... the upper and lower ... tract, and often causes ... and bullous or vesicular ... retinopathy Lab Tests