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differential rheumatology neurology autoimmune cauda caudaequina causes compylobacterjejuni equina erythematosus extremity flaccidpalsy gbs guillainbarresyndrome landrysyndrome lupus management myopathy pain sle
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Diagnosis Framework ... Sciatica • Tarsal tunnel ... • Myositis/pyomyositis ... #lower #extremity ... #msk #physicalexam
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... of Transverse Myelitis ... that results in CNS ... flexors of the legs ... negative, MOG-IgG test
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
(CES) is usually ... • Transverse myelitis ... lumbar stenosis • Vascular ... • Provocative Tests ... absent anal wink test
Guillain–Barré syndrome (GBS) (aka: Landry–Guillain–Barré–Strohl syndrome:  Most common cause of acute flaccid paralysis  Rapidly progressive ascending paralysis & areflexia  Autonomic
Guillain–Barré syndrome ... moves rapidly from lower ... Differential diagnosis ... Multiple Sclerosis: CNS ...  Transverse myelitis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... (hypertension, lower ... and CNS • Headache ... • Transverse Myelitis ... Erythematosus #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
arthralgia, arm/leg ... pulse deficits vascular ... the upper and lower ... legs), cutaneous ... chorioretinitis, CNS
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis ... Tests: • Measure ... INCLUSION BODY MYOSITIS ... lung disease • Myositis ... #Autoimmune #Myositis
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