56 results
Localizing Extraocular Movement Disorders
 • CN Ill (Oculomotor) Nerve Palsy 
 • CN IV (Trochlear) Nerve
) Nerve palsy ... ) Nerve palsy • ... One-and-a-half Syndrome ... #differential #diagnosis ... #ocular
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... Other brainstem syndromes ... • Transverse myelitis ... pain • Extra-CNS ... Manifestations #diagnosis
Differential diagnoses for the neuro-ophthalmologic finding of diplopia.
Neoplastic: 
 • Intraorbital meningioma 
 • Pituitary adenoma
Differential diagnoses ... VI palsy) • ... Miller-Fisher syndrome ... pseudotumor • Orbital myositis ... #Differential #Diagnosis
CN III Palsy - Oculomotor Nerve
 • Ptosis: Loss of innervation of the levator palpebrae superior.
CN III Palsy - Oculomotor ... comparison to Horner's syndrome ... neudrawlogy #CNIII #CN3 ... #Palsy #Oculomotor ... Cranial #neurology #diagnosis
Parkinson's Plus Syndromes - Atypical Parkinsonism
Main motor symptoms:
 • Tremors
 • Limb rigidity
 • Bradykinesia
Other symptoms
Parkinson's Plus Syndromes ... Parkinson's plus syndrome ... Progressive supranuclear palsy ... (CBS) • Dementia ... #Parkinsonism #diagnosis
Myositis Specific Antibodies (MSAs)

Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE
Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ
Immune Mediated
Myositis Specific ... Anti-Synthetase Syndrome ... Inclusion Body Myositis ... MSAs #clinical #diagnosis ... #rheumatology #
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... pulmonary etc) • CNS ... • Acute stroke syndromes ... Paraneoplastic syndrome ... #Differential #Diagnosis
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... anti-synthetase syndrome ... triad of ILD, myositis ... /full triad at diagnosis ... #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
ulceration • Ocular ... basal ganglia, CNS ... meningitis), MCC CNS ... collaboration • CNS ... signs #symptoms #rheumatology
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
- Differential Diagnosis ... three clinical diagnoses ... CN III palsy 2. ... • Third nerve palsy ... #Differential #Diagnosis