13 results
Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... • Transverse myelitis ... pain • Extra-CNS ... Systemic lupus erythematosus ... Manifestations #diagnosis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, macular, patchy ... Differential Diagnosis ... and CNS • Headache ... meningitis • Cranial ... • Transverse Myelitis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Polyneuropathy, Cranial ... Glomerulonephritis Myositis ... SLE #systemic #erythematosus ... signs #symptoms #diagnosis
Cranial Myokymia

Paroxysmal episodes of left facial (Orbicularis oculi) and left abducens spasms after remote radiation to
Cranial Myokymia ... facial (Orbicularis oculi ... @bobvarkey #Cranial ... video #neurology #physicalexam ... #CNVI #CN6 #Abducens
Ptosis - Differential Diagnosis Framework

Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
- Differential Diagnosis ... three clinical diagnoses ... CN III palsy 2. ... neuromuscular junction, cranial ... #Differential #Diagnosis
Photophobia and Headache - Differential Diagnosis Framework

Why?
• The coexistence of photophobia and headache suggests the potential
- Differential Diagnosis ... glaucoma - Ocular ... Trochlear headache • CNS ... Vasculitis Painful cranial ... #differential #diagnosis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... nervous system (CNS ... disease, myelopathy, cranial ... neuropathy, transverse myelitis ... • 8%-27% for CNS
Leg Pain - Differential Diagnosis Framework

Bone/Joint Causes of Leg Pain:
 • Fracture
 • Arthritis
 • Gout/pseudogout
- Differential Diagnosis ... Compartment syndrome • Myositis ... limb ischemia/cyanosis ... #differential #diagnosis ... extremity #msk #physicalexam
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... ischemia • Skin: Erythematous ... chorioretinitis, CNS ... Cogan syndrome: Ocular
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... blinks to threat Cranial ... • Vestibulo-ocular ... caseyalbin #PhysicalExam ... neurology #comatose #diagnosis