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diagnosis lupus neurology signs sle symptoms systemic abducens clinical cn6 cnvi differential management manifestations myokymia neuromyelitis nmo optica sjogrens syndrome
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... • Transverse myelitis ... pain • Extra-CNS ... positive NMO only): Myositis ... Systemic lupus erythematosus
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, macular, patchy ... Non-autoimmune rheumatologic ... and CNS • Headache ... meningitis • Cranial ... • Transverse Myelitis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Polyneuropathy, Cranial ... Glomerulonephritis Myositis ... SLE #systemic #erythematosus ... symptoms #diagnosis #rheumatology
Cranial Myokymia Paroxysmal episodes of left facial (Orbicularis oculi) and left abducens spasms after remote radiation to
Cranial Myokymia ... facial (Orbicularis oculi ... @bobvarkey #Cranial ... video #neurology #physicalexam ... #CNVI #CN6 #Abducens
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 Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... disease, myelopathy, cranial ... neuropathy, transverse myelitis ... • 8%-27% for CNS ... Sjogrens #Syndrome #Rheumatology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
ischemia • Skin: Erythematous ... ulcers, cutaneous, ocular ... chorioretinitis, CNS ... Cogan syndrome: Ocular ... Differential #Diagnosis #Rheumatology
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