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Neuromyelitis Optica (NMO) - Clinical Manifestations
 • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... • Transverse myelitis ... pain • Extra-CNS ... Systemic lupus erythematosus ... neurology #symptoms #signs
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
loss (50%) Eye: Sjögrens ... Polyneuropathy, Cranial ... Glomerulonephritis Myositis ... SLE #systemic #erythematosus ... #signs #symptoms
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
, macular, patchy ... dermatomyositis, Sjogren ... and CNS • Headache ... meningitis • Cranial ... • Transverse Myelitis
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... gland) biopsy • Ocular ... disease, myelopathy, cranial ... neuropathy, transverse myelitis ... • 8%-27% for CNS