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diagnosis management ophthalmology rheumatology signs symptoms abducens adies behcet cauda caudaequina causes clinical cn6 cnvi comatose disease disorders equina erythematosus
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... Other brainstem syndromes ... • Transverse myelitis ... pain • Extra-CNS ... Manifestations #diagnosis #neurology
Localizing Extraocular Movement Disorders • CN Ill (Oculomotor) Nerve Palsy • CN IV (Trochlear) Nerve
Nerve Palsy • CN ... One-and-a-half Syndrome ... ophthalmology #neurology ... #differential # ... diagnosis #ocular
Weakness - Differential Diagnosis Framework Approach To Weakness: • Non-neuromuscular disorder (Cardiac, pulmonary etc) • CNS ->
Weakness - Differential ... pulmonary etc) • CNS ... • Acute stroke syndromes ... #Weakness #Differential ... #Diagnosis #neurology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... skin injury) • Neurologic ... basal ganglia, CNS ... meningitis), MCC CNS ... Behcet disease) Differential
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Scleromyxedema (CNS ... +GI+CVS+joints) ... Hypergammaglobulinemic macular ... Hematology #Monoclonal #Differential
Ptosis - Differential Diagnosis Framework Ptosis (Greek- to fall) Drooping of the upper eyelid that usually results
Ptosis - Differential ... CN III palsy 2. ... Neurogenic Ptosis - Neurologic ... #Ptosis #neurology ... #Differential #
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis ... that results in CNS ... Pleocytosis > 100 cells ... diagnosis #management #neurology ... #differential
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... • Myositis/pyomyositis ... limb ischemia/cyanosis ... #Leg #pain #differential ... extremity #msk #physicalexam
Adie's Pupil What? Unknown nature & benign • Regular and mildly dilated pupil (4-6mm); • Light-near dissociaton;
Holmes-Adie Syndrome ... Young females Differential ... Diagnosis: • CN ... #Adies #Pupil #PhysicalExam ... #neurology #ophthalmology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Parotid swelling CNS ... nervous system (CNS ... neuropathy, transverse myelitis ... • 8%-27% for CNS
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