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differential rheumatology management neurology erythematosus lupus systemic aids cerebritis clues compylobacterjejuni flaccidpalsy gbs guillainbarresyndrome hematology hiv infections infectiousdiseases landrysyndrome leukemia
CNS Infection in HIV / AIDS - Differential Diagnosis Framework Principles of HIV-Associated CNS Opportunistic Infections: •
CNS Infection in ... HIV-Associated CNS ... Infections: • Most CNS ... • CNS opportunistic ... 100% Primary CNS
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... Erythematosus (SLE ... Demyelinating Syndrome, Headache ... autoantibodies that will cause ... #CNS #neurology
Guillain–Barré syndrome (GBS) (aka: Landry–Guillain–Barré–Strohl syndrome:  Most common cause of acute flaccid paralysis  Rapidly progressive ascending paralysis & areflexia  Autonomic
 Most common cause ... Differential diagnosis ... Multiple Sclerosis: CNS ... West Nile virus: Headache ...  Transverse myelitis
Signs and Symptoms Associated With Different Headache Etiologies • Nonfocal mental status changes - Meningitis, encephalitis,
stroke • Severe nausea ... pulsations on funduscopy ... movement deficits (CN ... signs #symptoms #clues ... #differential #diagnosis
Transverse Myelitis Overview Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
that results in CNS ... Myelitis Diagnosis ... Evaluate for NMO, SLE ... • Infectious causes ... Disorders: - SLE
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... Parotid swelling CNS ... nervous system (CNS ... peripheral neuropathy, transverse ... • 8%-27% for CNS
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
involvement • 30%: CNS ... -> AML: Blast crises ... Blast Phase: • Headaches ... leukostasis syndrome: CNS ... Hematology #Oncology #Diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... and CNS • Headache ... neuropathy • Transverse ... Erythematosus #Diagnosis
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... diseases, such as SLE ... 50 years • New headache ... tract, and often causes ... chorioretinitis, CNS
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